California Scientits Find new Substances to Fight Mosquitoes
2019-03-04 19:55

The sound of a mosquito can mean trouble in many parts of the world. The bite of the mosquito can be deadly. The insects carry serious diseases like malaria. The World Health Organization estimates that almost 630,000 people died from malaria and malaria-related causes in 2012, most of these cases were in African countries south of the Saharan desert.


In the United States, scientists are seeking new ways to fight malaria. A group of California scientists is working to develop a more effective and less costly substances to protect people from mosquito.


The researchers work at the University of California Riverside. They are investigating the sense of smell in mosquitoes. They found the insects use the same receptor for identifying carbon dioxide in human breath as they do for the smell of our skin.


Anandasankar Ray is leading the investigation. He says scientists tested more than a million chemical compounds until they found a substance called Ethyl pyruvate. He says Ethyl pyruvate makes the mosquitoes' receptor inactive.

Anandasankar Ray领导了这项研究。他说,科学家们测试了一百多万种化合物,直到他们发现一种被称为丙酮酸乙酯的化学物质,这种物质能够使蚊子的感受器失灵。

"When we apply Ethyl pyruvate to a human arm and offer it to hungry mosquitoes in a cage, then very few of the mosquitoes are attracted to the human arm because only a few of them are able to smell it out," said Ray.


Genevieve Tauxe is a member of the UC Riverside research team. She says it was not easy to find the neurons of noble cells that recognise both the smell of human breath and skin. She describes a device the researchers are using to examine mosquitoes.

吉纳维夫·托克斯(Genevieve Tauxe)是加州大学河滨分校研究团队的一员。她说,找到能同时识别人体呼吸和皮肤气味的神经元很不容易。她介绍了研究人员用来研究蚊子的仪器。

"With this apparatus, we are able to insert a very small electrode into the part of the mosquito's nose, effectively, where its olfactory neurons are and where the smell is happening," said Tauxe.


The scientists use these instruments to look for the signals that a mosquito's neurons send to its brain when it finds an interesting smell. Computer screen images show when the sense is strong or weak.


Anandasankar Ray says a product based on Ethyl pyruvate may cost less to manufacture than DEET, the most effective chemical treatment now in use. He says DEET is too costly for most people who live in areas affected by malaria.

Anandasankar Ray表示,基于丙酮酸乙酯的产品制造成本低于避蚊胺(DEET),避蚊胺是目前使用最为有效的化学方法。他说,避蚊胺对居住在受疟疾影响地区的人们来说过于昂贵。

"Perhaps by finding odors that can attack other target receptors, we will be able to improve upon DEET and finally have the next generation of insect behavior control products," said Ray.


The scientists believe they will soon be able to find a way to manufacture less costly and more effective products for the fight against mosquitoes.


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