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阿尔茨海默症治疗新方法

A New Approach to Alzheimer's
阿尔茨海默症治疗新方法
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2019-08-16 13:25
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阿尔茨海默症治疗新方法

Having witnessed the success of combination therapy in HIV, cancer and heart disease, the time has come for Alzheimer’s disease. At meetings convened by the Alzheimer’s Association and others, a consensus is emerging that the most effective Alzheimer’s treatments may be those that attack the disease on multiple fronts.

艾滋病、癌症和心脏病组合疗法成功经验证明,阿尔茨海默症治疗希望已经到来。在阿尔茨海默病协会和其他有关会议上,与会者取得共识,最有效治疗阿尔茨海默症的方法是同时攻克疾病多重难点。

Looking back for a moment… In the 1980s, the world faced a new, unknown virus. HIV/AIDS was spreading virtually unchecked, devastating millions of lives and spurring lively scientific debate. Today, an HIV diagnosis is no longer a death sentence. AIDS-related deaths have fallen by 45 percent since their peak in 2005 according to UNAIDS, a United Nations program for global action against the spread of the virus. 

回忆过去20世纪80年代,世界面临着一个未知病毒造成数百万人死亡,科学界大为震惊。这就是艾滋病毒/艾滋病扩散没有被检测发现。今天,艾滋病毒携带者不再被判死刑。根据联合国艾滋病规划署(UNAIDS)资料,艾滋病死亡人数已从2005年高位下降了45%。

As researchers learned more about HIV, they developed new classes of antiviral medications—each attacking the virus in a unique way. Physicians eventually began prescribing two or more of these drugs together and emerging scientific evidence started revealing the most effective combinations. Today, a powerful three-drug antiviral “cocktail” is allowing people with HIV to live long lives.

随着对艾滋病毒深入了解,研究人员开发出多种抗病毒药物,每一种药物各具特点。现在,医生开出的处方有二种或二种以上药物。研究证明,这种组合疗法效果特好。现在,有一种三药抗病毒“鸡尾酒”疗法,给艾滋病毒感染者带来更长生存时间。

Advances in understanding the progression of Alzheimer’s point to a number of underlying biological processes involved in the development of the disease. By leveraging this knowledge, we now have a singular opportunity to pioneer new approaches against Alzheimer’s, including combination therapies.

阿尔茨海默症的形成和发展涉及许多生物过程,这是认识上的进步。利用这些知识,给阿尔茨海默症治疗找到新方法提供绝好机会,其中包括综合疗法。

The Alzheimer’s Association has partnered with the Alzheimer’s Drug Discovery Foundation (ADDF) to challenge the research community to propose promising drug combinations to find more-effective treatments.

阿尔茨海默症协会与药物发现基金会(ADDF)合作,为获得最有效治疗方法,提出了药物组合建议,得到研究部门重视。

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